Prof. Jörg Vogel
Über
Prof. Jörg Vogel ist seit 2017 Direktor des Helmholtz-Instituts für RNA-basierte Infektionsforschung (HIRI) in Würzburg, wo er schon seit 2009 als Professor und Direktor des Instituts für Molekulare Infektionsbiologie (IMIB) tätig war. Als weltweit anerkannter Wissenschaftler auf dem Gebiet der RNA-Biologie, 2017 mit dem Leibniz-Preis ausgezeichnet, gilt er als Pionier in der Anwendung und Entwicklung von Hochdurchsatz-Sequenziermethoden für die Analyse einzelner infizierter Zellen sowie von Interaktionen zwischen krankheitserregenden Bakterien und ihren Wirten. Er studierte Biochemie an der Humboldt-Universität zu Berlin und am Imperial College, London (GB). 1999 promovierte er an der Humboldt-Universität mit einer Dissertation über
Gruppe II-Intronspleißen . Er forschte 2000/2001 an der Universität Uppsala (Schweden) und 2002/2003 als EMBO-Fellow an der Hebrew University, Jerusalem (Israel), bevor er 2004 eine unabhängige Nachwuchsgruppe am Max-Planck-Institut für Infektionsbiologie in Berlin gründete.
2023
Grad-seq analysis of Enterococcus faecalis and Enterococcus faecium provides a global view of RNA and protein complexes in these two opportunistic pathogens
Michaux C, Gerovac M, Hansen EE, Barquist L, Vogel J (2023)
microLife 4: 027DOI: 10.1093/femsml/uqac027
Gut Microbiota Contribution to Weight-Independent Glycemic Improvements after Gastric Bypass Surgery
Hankir MK, Kovatcheva-Datchary P, Springer R, Hoffmann A, Vogel J, Seyfried F, Arora T (2023)
Microbiology Spectrum (Online ahead of print)DOI: 10.1128/spectrum.05109-22
Improved Bacterial Single-Cell RNA-Seq through Automated MATQ-Seq and Cas9-Based Removal of rRNA Reads
Homberger C, Hayward RJ, Barquist L, Vogel J (2023)
mBio (Online ahead of print)DOI: 10.1128/mbio.03557-22
A primary cell-based in vitro model of the human small intestine reveals host olfactomedin 4 induction in response to Salmonella Typhimurium infection
Däullary T, Imdahl F, Dietrich O, Hepp L, Krammer T, Fey C, Neuhaus W, Metzger M, Vogel J, Westermann AJ, Saliba AE, Zdzieblo D (2023)
Gut Microbes 15 (1): 2186109DOI: 10.1080/19490976.2023.2186109
Design and off-target prediction for antisense oligomers targeting bacterial mRNAs with the MASON webserver
Jung JJ, Popella L, Do PT, Pfau P, Vogel J, Barquist L (2023)
RNA (Online ahead of print)DOI: 10.1261/rna.079263.122
RNA recording in single bacterial cells using reprogrammed tracrRNAs
Jiao C, Reckstadt C, König F, Homberger C, Yu J, Vogel J, Westermann AJ, Sharma CM, Beisel CL (2023)
Nature Biotechnology (Online ahead of print)DOI: 10.1038/s41587-022-01604-8
A MATQ-seq-Based Protocol for Single-Cell RNA-seq in Bacteria
Homberger C, Saliba AE, Vogel J (2023)
Methods in Molecular Biology 2584: 105-121DOI: 10.1007/978-1-0716-2756-3_4
2022
Ushering in a new era of single-cell transcriptomics in bacteria
Homberger C, Barquist L, Vogel J (2022)
microLife 3: 020DOI: 10.1093/femsml/uqac020
Hypothalamic integrity is necessary for sustained weight loss after bariatric surgery: A prospective, cross-sectional study
Dischinger U, Kötzner L, Kovatcheva-Datchary P, Kleinschmidt H, Haas C, Perez J, Presek C, Koschker AC, Miras AD, Hankir MK, …, Herrmann MJ, Seyfried F (2022)
Metabolism: Clinical and Experimental 138: 155341DOI: 10.1016/j.metabol.2022.155341
Global profiling of the RNA and protein complexes of Escherichia coli by size exclusion chromatography followed by RNA sequencing and mass spectrometry (SEC-seq)
Chihara K, Gerovac M, Hör J, Vogel J (2022)
RNA (Online ahead of print)DOI: 10.1261/rna.079439.122
An unusual mode of baseline translation adjusts cellular protein synthesis capacity to metabolic needs
Schneider C, Erhard F, Binotti B, Buchberger A, Vogel J, Fischer U (2022)
Cell Reports 41 (2): 111467DOI: 10.1016/j.celrep.2022.111467
INRI-seq enables global cell-free analysis of translation initiation and off-target effects of antisense inhibitors
Hör J, Jung J, Ðurica-Mitic S, Barquist L, Vogel J (2022)
Nucleic Acids Research 50 (22): 128DOI: 10.1093/nar/gkac838
Expanding the genetic toolkit helps dissect a global stress response in the early-branching species Fusobacterium nucleatum
Ponath F, Zhu Y, Cosi V, Vogel J (2022)
PNAS 119 (40): 2201460DOI: 10.1073/pnas.2201460119
TFEB induces mitochondrial itaconate synthesis to suppress bacterial growth in macrophages
Schuster EM, Epple MW, Glaser KM, Mihlan M, Lucht K, Zimmermann JA, Bremser A, Polyzou A, Obier N, Cabezas-Wallscheid N, …, Westermann AJ, Rambold AS (2022)
Nature Metabolism 4 (7): 856-866DOI: 10.1038/s42255-022-00605-w
Comprehensive analysis of PNA-based antisense antibiotics targeting various essential genes in uropathogenic Escherichia coli
Popella L, Jung J, Do PT, Hayward RJ, Barquist L, Vogel J (2022)
Nucleic Acids Research 50 (11): 6435DOI: 10.1093/nar/gkac362
Cellular RNA Targets of Cold Shock Proteins CspC and CspE and Their Importance for Serum Resistance in Septicemic Escherichia coli
Yair Y, Michaux C, Biran D, Bernhard J, Vogel J, Barquist L, Ron EZ (2022)
mSystems 7 (4): 0008622DOI: 10.1128/msystems.00086-22
An overview of gene regulation in bacteria by small RNAs derived from mRNA 3' ends
Ponath F, Hör J, Vogel J (2022)
FEMS Microbiology Reviews 46 (5): 017DOI: 10.1093/femsre/fuac017
Global RNA interactome of Salmonella discovers a 5' UTR sponge for the MicF small RNA that connects membrane permeability to transport capacity
Matera G, Altuvia Y, Gerovac M, El Mouali Y, Margalit H, Vogel J (2022)
Molecular Cell 82 (3): 629-644DOI: 10.1016/j.molcel.2021.12.030
The DNA polymerase of bacteriophage YerA41 replicates its T-modified DNA in a primer-independent manner
Gomez-Raya-Vilanova MV, Leskinen K, Bhattacharjee A, Virta P, Rosenqvist P, Smith JLR, Bayfield OW, Homberger C, Kerrinnes T, Vogel J, Pajunen MI, Skurnik M (2022)
Nucleic Acids Research 50 (7): 3985-3997DOI: 10.1093/nar/gkac203
Innovative developments and emerging technologies in RNA therapeutics
Halloy F, Biscans A, Bujold KE, Debacker A, Hill AC, Lacroix A, Luige O, Strömberg R, Sundstrom L, Vogel J, Ghidini A (2022)
RNA Biology 19 (1): 313-332DOI: 10.1080/15476286.2022.2027150