Our mission is to pursue scientific research without boundaries. We want the research we produce to be accessible and reproducible. The main outputs of our research are new ideas, knowledge and techniques, which we publish as peer-reviewed research publications. Maximising the sharing of our research is the best way of ensuring that people can access, read and develop upon it.

Publication Highlights

Have a look at what we have recently discovered.

garv - Redmond Smyth

The evolution of RNA structural probing methods: From gels to next-generation sequencing

Mailler E, Paillart J, Marquet R, Smyth R, Vivet-Boudou V, (2019)

Wiley Interdiscip. Rev. RNA, 10, 2, 10.1002/wrna.1518, 30485688

Structural and Functional Motifs in Influenza Virus RNAs

Ferhadian D, Contrant M, Printz-Schweigert A, Smyth R, Paillart J, Marquet R, (2018)

Frontiers in microbiology, 9, 10.3389/fmicb.2018.00559, 29651275

In cell mutational interference mapping experiment (in cell MIME) identifies the 5' polyadenylation signal as a dual regulator of HIV-1 genomic RNA production and packaging

Smyth R, Smith M, Jousset A, Despons L, Laumond G, Decoville T, Cattenoz P, Moog C, Jossinet F, Marquet R... (2018)

Nucleic acids research, 46, 9, 10.1093/nar/gky152, 29514260

RNA Structure - A Neglected Puppet Master for the Evolution of Virus and Host Immunity

Smyth R, Negroni M, Lever A, Mak J, Kenyon J, (2018)

Front. Immunol., 9, 10.3389/fimmu.2018.02097,

hopi - Alexander Westermann

Induced Pluripotent Stem Cell-Derived Brain Endothelial Cells as a Cellular Model to Study Neisseria meningitidis Infection

Martins Gomes S, Westermann A, Sauerwein T, Hertlein T, Förstner K, Ohlsen K, Metzger M, Shusta E, Kim B, Schubert-Unkmeir A... (2019)

Front. Microbiol., 10, 10.3389/fmicb.2019.01181, 31191497

Regulatory RNAs in Virulence and Host-Microbe Interactions

Westermann A, (2018)

Contribution, 6, 4, 305-337, 10.1128/microbiolspec.RWR-0002-2017, 30003867

Toward Cell Type-Specific In Vivo Dual RNA-Seq

Frönicke L, Bronner D, Byndloss M, McLaughlin B, Bäumler A, Westermann A, (2018)

Meth. Enzymol., 612, 505-522, 10.1016/bs.mie.2018.08.013, 30502956

Host-Pathogen Transcriptomics by Dual RNA-Seq

Westermann A, Vogel J, (2018)

Contribution, 1737, 59-75, 10.1007/978-1-4939-7634-8_4, 29484587

MetaMap: an atlas of metatranscriptomic reads in human disease-related RNA-seq data

Simon L, Karg S, Westermann A, Engel M, Elbehery A, Hense B, Heinig M, Deng L, Theis F, (2018)

Gigascience, 7, 6, 10.1093/gigascience/giy070, 29901703

iiib - Lars Barquist

Rapid transcriptional responses to serum exposure are associated with sensitivity and resistance to antibody-mediated complement killing in invasive Salmonella Typhimurium ST313

Ondari E, Klemm E, Msefula C, El Ghany M, Heath J, Pickard D, Barquist L, Dougan G, Kingsley R, MacLennan C... (2019)

Wellcome Open Res., 4, 10.12688/wellcomeopenres.15059.1, 31231691

Transcriptional noise and exaptation as sources for bacterial sRNAs

Jose B, Gardner P, Barquist L, (2019)

Biochem. Soc. Trans., 47, 2, 527-539, 10.1042/BST20180171, 30837318

Global Maps of ProQ Binding In Vivo Reveal Target Recognition via RNA Structure and Stability Control at mRNA 3' Ends

Holmqvist E, Li L, Bischler T, Barquist L, Vogel J, (2018)

Molecular cell, 70, 5, 971-982, 10.1016/j.molcel.2018.04.017, 29804828

A global genomic approach uncovers novel components for twitching motility-mediated biofilm expansion in Pseudomonas aeruginosa

Nolan L, Whitchurch C, Barquist L, Katrib M, Boinett C, Mayho M, Goulding D, Charles I, Filloux A, Cain A... (2018)

Microb. Genom., 4, 11, 10.1099/mgen.0.000229, 30383525

Morphological, genomic and transcriptomic responses of Klebsiella pneumoniae to the last-line antibiotic colistin

Cain A, Boinett C, Barquist L, Dordel J, Fookes M, Mayho M, Ellington M, Goulding D, Pickard D, Thomson N... (2018)

Scientific reports, 8, 1, 10.1038/s41598-018-28199-y, 29959380

lrib - Mathias Munschauer

Nuclear lncRNA stabilization in the host response to bacterial infection

Munschauer M, Vogel J, (2018)

The EMBO journal, 37, 13, 10.15252/embj.201899875, 29934294

Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis

Khajuria R, Munschauer M, Ulirsch J, Fiorini C, Ludwig L, McFarland S, Abdulhay N, Specht H, Keshishian H, Sankaran V... (2018)

Cell, 173, 1, 90-103, 10.1016/j.cell.2018.02.036, 29551269

New insights into the cellular temporal response to proteostatic stress

Rendleman J, Cheng Z, Maity S, Kastelic N, Munschauer M, Allgoewer K, Teo G, Zhang Y, Lei A, Vogel C... (2018)

Elife, 7, 10.7554/eLife.39054, 30272558

The NORAD lncRNA assembles a topoisomerase complex critical for genome stability

Munschauer M, Nguyen C, Sirokman K, Hartigan C, Hogstrom L, Engreitz J, Ulirsch J, Fulco C, Subramanian V, Lander E... (2018)

Nature, 561, 7721, 132-136, 10.1038/s41586-018-0453-z, 30150775

Um unsere Webseite für Sie optimal zu gestalten und fortlaufend verbessern zu können, verwenden wir Cookies. Wenn Sie die Website weiter nutzen, gehen wir von Ihrem Einverständnis aus. Mehr Informationen