Dr Antoine-Emmanuel Saliba


Antoine-Emmanuel Saliba studied biochemical engineering at INSA Toulouse (France) and received his PhD in the research group of Jean-Louis Viovy at the Institut Curie (Paris, France). During this time, he developed microfluid-based systems for sorting and analysing rare subpopulations of cancer cells. He then worked as an EIPOD fellow at the European Molecular Biology Laboratory (Heidelberg, Germany) and was involved in the development of innovative systems biology methods for the analysis of protein-lipid interactions. He then joined Jörg Vogel's laboratory in Würzburg as a senior postdoctoral fellow and established single-cell RNA-sequencing to track the fate of individual cells during an infection with Salmonella enterica. Since 2017 he has led the Single-cell Analysis group at HIRI.


Dynamics of Cardiac Neutrophil Diversity in Murine Myocardial Infarction

Vafadarnejad E, Rizzo G, Krampert L, Arampatzi P, Arias-Loza A, Nazzal Y, Rizakou A, Knochenhauer T, Bandi SR, Nugroho VA, …, Saliba AE, Cochain C (2020)

Circulation Research 127 (9): 232-249DOI: 10.1161/CIRCRESAHA.120.317200

Single-cell RNA-sequencing reports growth-condition-specific global transcriptomes of individual bacteria

Imdahl F, Vafadarnejad E, Homberger C, Saliba AE, Vogel J (2020)

Nature Microbiology 5 (10): 1202DOI: 10.1038/s41564-020-0774-1

Severe COVID-19 is marked by a dysregulated myeloid cell compartment

Schulte-Schrepping J, Reusch N, Paclik D, Baßler K, Schlickeiser S, Zhang B, Krämer B, Krammer T, Brumhard S, Bonaguro L, …, Saliba AE, Sander LE (2020)

Cell 182 (6): 1419-1440DOI: 10.1016/j.cell.2020.08.001

Tracheal brush cells release acetylcholine in response to bitter tastants for paracrine and autocrine signaling

Hollenhorst MI, Jurastow I, Nandigama R, Appenzeller S, Li L, Vogel J, Wiederhold S, Althaus M, Empting M, Altmüller J, …, Saliba AE, Krasteva-Christ G (2020)

The FASEB Journal 34 (1): 316-332DOI: 10.1096/fj.201901314RR

Eleven grand challenges in single-cell data science

Lähnemann D, Köster J, Szczurek E, McCarthy DJ, Hicks SC, Robinson MD, Vallejos CA, Campbell KR, Beerenwinkel N, Mahfouz A, …, Shah SP, Schönhuth A (2020)

Genome Biology 21: 31DOI: 10.1186/s13059-020-1926-6


scSLAM-seq reveals core features of transcription dynamics in single cells

Erhard F, Baptista MA, Krammer T, Hennig T, Lange M, Arampatzi P, Jürges CS, Theis FJ, Saliba AE, Dölken L (2019)

Nature 571 (7765): 419-423DOI: 10.1038/s41586-019-1369-y