Dr Antoine-Emmanuel Saliba


Antoine-Emmanuel Saliba studied biochemical engineering at INSA Toulouse (France) and received his PhD in the research group of Jean-Louis Viovy at the Institut Curie (Paris, France). During this time, he developed microfluid-based systems for sorting and analysing rare subpopulations of cancer cells. He then worked as an EIPOD fellow at the European Molecular Biology Laboratory (Heidelberg, Germany) and was involved in the development of innovative systems biology methods for the analysis of protein-lipid interactions. He then joined Jörg Vogel's laboratory in Würzburg as a senior postdoctoral fellow and established single-cell RNA-sequencing to track the fate of individual cells during an infection with Salmonella enterica. Since 2017 he has led the Single-cell Analysis group at HIRI.

hopi - Alexander Westermann

Einzelzell-RNA-Sequenzierung beleuchtet den Infektionsprozess

Saliba A, Westermann A, Vogel J, (2017)

Biospektrum, 23, 5, 525-528, 10.1007/s12268-017-0836-y,

Single-cell RNA-seq: advances and future challenges

Saliba A, Westermann A, Gorski S, Vogel J, (2014)

Nucleic acids research, 42, 14, 8845-60, 10.1093/nar/gku555, 25053837

rabi - Jörg Vogel

Salmonella persisters undermine host immune defenses during antibiotic treatment

Stapels D, Hill P, Westermann A, Fisher R, Thurston T, Saliba A, Blommestein I, Vogel J, Helaine S, (2018)

Science (New York, N.Y.), 362, 6419, 1156-1160, 10.1126/science.aat7148, 30523110

Genome organization and DNA accessibility control antigenic variation in trypanosomes

Müller L, Cosentino R, Förstner K, Guizetti J, Wedel C, Kaplan N, Janzen C, Arampatzi P, Vogel J, Siegel T... (2018)

Nature, 563, 7729, 121-125, 10.1038/s41586-018-0619-8, 30333624

Single-cell RNA-seq ties macrophage polarization to growth rate of intracellular Salmonella

Saliba A, Li L, Westermann A, Appenzeller S, Stapels D, Schulte L, Helaine S, Vogel J, (2016)

Nature microbiology, 2, 10.1038/nmicrobiol.2016.206, 27841856

siga - Emmanuel Saliba

scSLAM-seq reveals core features of transcription dynamics in single cells

Erhard F, Baptista M, Krammer T, Hennig T, Lange M, Arampatzi P, Jürges C, Theis F, Saliba A, Dölken L... (2019)

Nature, 571, 7765, 419-423, 10.1038/s41586-019-1369-y, 31292545

Atlas of the Immune Cell Repertoire in Mouse Atherosclerosis Defined by Single-Cell RNA-Sequencing and Mass Cytometry

Winkels H, Ehinger E, Vassallo M, Buscher K, Dinh H, Kobiyama K, Hamers A, Cochain C, Vafadarnejad E, Wolf D... (2018)

Circ. Res., 122, 12, 1675-1688, 10.1161/CIRCRESAHA.117.312513., 29545366

Neonatally imprinted stromal cell subsets induce tolerogenic dendritic cells in mesenteric lymph nodes

Pezoldt J, Pasztoi M, Zou M, Wiechers C, Beckstette M, Thierry G, Vafadarnejad E, Floess S, Arampatzi P, Huehn J... (2018)

Nat. Commun., 9, 1, 10.1038/s41467-018-06423-7, 30254319

Single-Cell RNA-Seq Reveals the Transcriptional Landscape and Heterogeneity of Aortic Macrophages in Murine Atherosclerosis

Cochain C, Vafadarnejad E, Arampatzi P, Pelisek J, Winkels H, Ley K, Wolf D, Saliba A, Zernecke A, (2018)

Circ. Res., 122, 12, 1661-1674, 10.1161/CIRCRESAHA.117.312509, 29545365

New RNA-seq approaches for the study of bacterial pathogens

Saliba A, C Santos S, Vogel J, (2017)

Current opinion in microbiology, 35, 78-87, 10.1016/j.mib.2017.01.001, 28214646

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