Dr Chunyu Liao
About
Chunyu obtained her PhD degree in Microbiology from Iowa State University in December 2015. During her PhD study with Dr Laura Jarboe, she worked on exploring genetic factors driving attachment of bacteria to environmental particles. As a PostDoc in the Beisel lab, her current research focused on investigating mechanisms of crRNA biogenesis and developing tools for CRISPR-based high-throughput screens.
2019
CRATES: A one-step assembly method for Class 2 CRISPR arrays
Liao C, Slotkowski R, Beisel C (2019)
Methods In Enzymology, 629: 493-511DOI: 10.1016/bs.mie.2019.04.011
Modular one-pot assembly of CRISPR arrays enables library generation and reveals factors influencing crRNA biogenesis
Liao C, Ttofali F, Slotkowski R, Denny S, Cecil T, Leenay R, Keung A, Beisel C (2019)
Nature Communications, 10 (1): 2948DOI: 10.1038/s41467-019-10747-3
The Acidaminococcus sp. Cas12a nuclease recognizes GTTV and GCTV as non-canonical PAMs
Jacobsen T, Liao C, Beisel C (2019)
FEMS Microbiology Letters, 366 (8): 085DOI: 10.1093/femsle/fnz085
2018
The Francisella novicida Cas12a is sensitive to the structure downstream of the terminal repeat in CRISPR arrays
Liao C, Slotkowski R, Achmedov T, Beisel C (2018)
RNA Biology, 16 (4): 404-412DOI: 10.1080/15476286.2018.1526537