Prof Antoine-Emmanuel Saliba
About
Antoine-Emmanuel Saliba studied biochemical engineering at INSA Toulouse (France) and received his PhD in the research group of Jean-Louis Viovy at the Institut Curie (Paris, France). During this time, he developed microfluid-based systems for sorting and analysing rare subpopulations of cancer cells. He then worked as an EIPOD fellow at the European Molecular Biology Laboratory (Heidelberg, Germany) and was involved in the development of innovative systems biology methods for the analysis of protein-lipid interactions. He then joined Jörg Vogel's laboratory in Würzburg as a senior postdoctoral fellow and established single-cell RNA-sequencing to track the fate of individual cells during an infection with Salmonella enterica. Since 2017, he has led the Single-cell Analysis group at HIRI. As of 2023, he also holds a professorship (W2) at the Faculty of Medicine of the University of Würzburg.
2026
Uropathogenic Escherichia coli invade luminal prostate cells via FimH-PPAP receptor binding
Guedes M, Peters S, Joshi A, Dorn S, Rieger J, Klapproth K, Beste T, Leipold AM, Rosenfeldt M, Saliba AE, …, Kalogirou C, Aguilar C (2026)
Nature Microbiology Online ahead of printDOI: 10.1038/s41564-025-02231-0
2025
Allogeneic hematopoietic cell transplantation initiates atherosclerosis in mice via CD8+ T cells // Allogeneic haematopoietic cell transplantation promotes atherosclerosis in mice via CD8+ T cells
Jorgacevic I, Shaikh H, Ali H, Bundalo M, Schäfer S, Kern MAG, Büttner-Herold M, Reu-Hofer S, Cochain C, Bartolomaeus H, …, Beilhack A, Zernecke A (2025)
Cardiovascular Research 121 (17): 2668-2678DOI: 10.1093/cvr/cvaf229
Targeted DNA ADP-ribosylation triggers templated repair in bacteria and base mutagenesis in eukaryotes
Gupta D, Patinios C, Bassett HV, Kibe A, Collins SP, Kamm C, Wang Y, Zhao C, Vollen K, Toussaint C, …, Schut F, Corn JE (2025)
Nature Biotechnology (Online ahead of print)DOI: 10.1038/s41587-025-02802-w
Low-input RNA-seq suggests metabolic specialization underlying morphological heterogeneity in a gut commensal bacterium
Bornet E, Prezza G, Cecchino L, Jenniches L, Behrends J, Tawk C, Huang KC, Strowig T, Vogel J, Barquist L, Saliba AE, Westermann AJ (2025)
Cell Reports 44 (6): 115844DOI: 10.1016/j.celrep.2025.115844
A distinct priming phase regulates CD8 T cell immunity by orchestrating paracrine IL-2 signals
Jobin K, Seetharama D, Rüttger L, Fenton C, Kharybina E, Wirsching A, Huang A, Knöpper K, Kaisho T, Busch DH, …, Gasteiger G, Kastenmüller W (2025)
Science 388 (6743): eadq1405DOI: 10.1126/science.adq1405
Resolving spatiotemporal dynamics in bacterial multicellular populations: approaches and challenges
Espinoza Miranda SS, Abbaszade G, Hess WR, Drescher K, Saliba AE, Zaburdaev V, Chai L, Dreisewerd K, Grünberger A, Westendorf C, Müller S, Mascher T (2025)
Microbiology and Molecular Biology Reviews 89 (1): e0013824DOI: 10.1128/mmbr.00138-24