Research at the interface of RNA & Infection

Rising antimicrobial resistance, chronic infections, and (re-) emerging pathogens are among the major challenges facing humanity. RNA is increasingly understood to contribute to key regulatory and sensory processes in the cell, but the role of RNA in infection biology remains understudied.

Research at HIRI aims to close this gap by combining interdisciplinary expertise with cutting-edge research infrastructure to exploit the vast potential of RNA as a diagnostic molecule, target, and drug to combat infectious disease.

our major goals are

Developing innovative delivery techniques for RNA-based interventions

Understanding RNA-based mechanisms in virulence and host defence

Identifying novel regulatory RNAs with key roles in pathogenesis

Resolving the complexity and heterogeneity of infection processes at the single-cell level

Exploiting RNA knowledge for new diagnostics, preventives, and anti-infectives