Graduate Program

Long-forgotten pathogens are experiencing a renaissance, and new ones are constantly emerging—infectious diseases represent a major challenge for society in the 21st century. At the same time, antibiotic resistance is on the rise: conventional antibiotic therapies continue to fail in many clinical settings. Thus, novel therapeutic options are urgently needed. RNA-based drugs could offer a solution.

PhD students at the Helmholtz Institute Würzburg perform basic research on the role RNA plays in pathogens and infected hosts. Their ultimate goal is to leverage the vast potential of RNA as a diagnostic, target, and drug to combat infectious diseases, such as those caused by SARS-CoV-2 or multidrug-resistant bacteria. Examples include developing new single-cell technologies as well as RNA-seq- and CRISPR-based methodologies to visualize and interrogate infection processes.

UNIQUE FEATURES OF THE PROGRAM: LAB ROTATIONS AND A FLEXIBLE START DATE

The HIRI PhD program is highly unique as we offer fully-funded positions independent of any lab or project. At first, students participate in three short lab rotations. This allows them to get a glimpse of the science pursued and techniques used in the respective labs. An individual matchmaking process after the rotations ensures that students find the right supervisor and start shaping their PhD project. In addition, we offer flexible start dates to admitted students, again supporting individual needs and requirements.

Our students receive structured mentoring and training throughout their PhD, including short intensive courses in RNA and infection biology, annual scientific retreats, and opportunities to present their research at international conferences. They will receive thorough training in state-of-the-art techniques like RNA- and single-cell sequencing, CRISPR-Cas genome editing, and machine learning—and leverage this knowledge toward the understanding of the role of RNA in infection processes.

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How to apply

Introducing our PhD students

Typical “RNA & Infection” students will hold an MSc (or equivalent) in molecular or cell biology, microbiology, biochemistry, bioinformatics, bioengineering, or related fields. We expect to see a strong academic and scientific track record. Solid background knowledge in RNA biology, microbiology, virology, cell biology, host-pathogen-interaction, single-cell analysis, bioinformatics, or biochemistry is preferred.

We are looking for candidates with good English communication and presentation skills (written and spoken). Furthermore, we expect our prospective PhD students to have intercultural competence paired with self-motivation and enthusiasm, as well as a strong desire to do research at the interface of RNA and infection biology.