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Improved RNA stability estimation through Bayesian modeling reveals most Salmonella transcripts have subminute half-lives
Publication
Jenniches L,
Michaux C,
Popella L,
Reichardt S,
Vogel J,
Westermann AJ,
Barquist L
(2024)
Proceedings of the National Academy of Sciences of the United States of America, 121, 14, e2308814121, 10.1073/pnas.2308814121, 38527194
Proceedings of the National Academy of Sciences of the United States of America, 121, 14, e2308814121, 10.1073/pnas.2308814121, 38527194
RNA target profiles direct the discovery of virulence functions for the cold-shock proteins CspC and CspE
Publication
Michaux C,
Holmqvist E,
Vasicek E,
Sharan M,
Barquist L,
Westermann AJ,
Gunn JS,
Vogel J
(2017)
PNAS, 114, 26, 6824-6829, 10.1073/pnas.1620772114, 28611217
PNAS, 114, 26, 6824-6829, 10.1073/pnas.1620772114, 28611217
Single-cell RNA-seq ties macrophage polarization to growth rate of intracellular Salmonella
Publication
Saliba AE,
Li L,
Westermann AJ,
Appenzeller S,
Stapels DA,
Schulte LN,
Helaine S,
Vogel J
(2016)
Nature Microbiology, 2, 16206, 10.1038/nmicrobiol.2016.206, 27841856
Nature Microbiology, 2, 16206, 10.1038/nmicrobiol.2016.206, 27841856
Grad-seq identifies KhpB as a global RNA-binding protein in Clostridioides difficile that regulates toxin production
Publication
Lamm-Schmidt V,
Fuchs M,
Sulzer J,
Gerovac M,
Hör J,
Dersch P,
Vogel J,
Faber F
(2021)
microLife, 2, uqab004, 10.1093/femsml/uqab004
microLife, 2, uqab004, 10.1093/femsml/uqab004
RNA recording in single bacterial cells using reprogrammed tracrRNAs
Publication
Jiao C,
Reckstadt C,
König F,
Homberger C,
Yu J,
Vogel J,
Westermann AJ,
Sharma CM,
Beisel CL
(2023)
Nature Biotechnology, 41, 8, 1107-1116, 10.1038/s41587-022-01604-8, 36604543
Nature Biotechnology, 41, 8, 1107-1116, 10.1038/s41587-022-01604-8, 36604543
Salmonella persisters undermine host immune defenses during antibiotic treatment
Publication
Stapels DA,
Hill PW,
Westermann AJ,
Fisher RA,
Thurston TL,
Saliba AE,
Blommestein I,
Vogel J,
Helaine S
(2018)
Science, 362, 6419, 1156-1160, 10.1126/science.aat7148, 30523110
Science, 362, 6419, 1156-1160, 10.1126/science.aat7148, 30523110
Dual RNA-seq unveils noncoding RNA functions in host-pathogen interactions
Publication
Westermann AJ,
Forstner KU,
Amman F,
Barquist L,
Chao Y,
Schulte LN,
Muller L,
Reinhardt R,
Stadler PF,
Vogel J
(2016)
Nature, 529, 7587, 496-501, 10.1038/nature16547, 26789254
Nature, 529, 7587, 496-501, 10.1038/nature16547, 26789254
An RNA-centric global view of Clostridioides difficile reveals broad activity of Hfq in a clinically important gram-positive bacterium
Publication
Fuchs M,
Lamm-Schmidt V,
Sulzer J,
Ponath F,
Jenniches L,
Kirk JA,
Fagan RP,
Barquist L,
Vogel J,
Faber F
(2021)
PNAS, 118, 25, e2103579118, 10.1073/pnas.2103579118, 34131082
PNAS, 118, 25, e2103579118, 10.1073/pnas.2103579118, 34131082
A primary cell-based in vitro model of the human small intestine reveals host olfactomedin 4 induction in response to Salmonella Typhimurium infection
Publication
Däullary T,
Imdahl F,
Dietrich O,
Hepp L,
Krammer T,
Fey C,
Neuhaus W,
Metzger M,
Vogel J,
Westermann AJ,
Saliba AE,
Zdzieblo D
(2023)
Gut Microbes, 15, 1, 2186109, 10.1080/19490976.2023.2186109, 36939013
Gut Microbes, 15, 1, 2186109, 10.1080/19490976.2023.2186109, 36939013
Dual RNA-seq of Orientia tsutsugamushi informs on host-pathogen interactions for this neglected intracellular human pathogen
Publication
Mika-Gospodorz B,
Giengkam S,
Westermann AJ,
Wongsantichon J,
Kion-Crosby W,
Chuenklin S,
Wang LC,
Sunyakumthorn P,
Sobota RM,
Subbian S,
Vogel J,
Barquist L,
Salje J
(2020)
Nature Communications, 11, 3363, 10.1038/s41467-020-17094-8, 32620750
Nature Communications, 11, 3363, 10.1038/s41467-020-17094-8, 32620750