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Designing the Aplysia punctata Arginine-Depleting Enzyme for Tumor Targeting
Publikation
Wolkersdorfer AM,
Endo Y,
Kehrein J,
Kappus M,
Hattori S,
Gutmann M,
Rudel T,
Caliskan N,
Lühmann T,
Kato Y,
Meinel L
(2025)
Molecular Pharmaceutics, 22, 3, 1253–1261, 10.1021/acs.molpharmaceut.4c00964, 39950605
Molecular Pharmaceutics, 22, 3, 1253–1261, 10.1021/acs.molpharmaceut.4c00964, 39950605
Disparate mechanisms counteract extraneous CRISPR RNA production in type II-C CRISPR-Cas systems
Publikation
Feussner M,
Migur A,
Mitrofanov A,
Alkhnbashi OS,
Backofen R,
Beisel CL,
Weinberg Z
(2025)
microLife, 6, uqaf007, 10.1093/femsml/uqaf007, 40376300
microLife, 6, uqaf007, 10.1093/femsml/uqaf007, 40376300
A Multicellular In Vitro Model of the Human Intestine with Immunocompetent Features Highlights Host-Pathogen Interactions During Early Salmonella Typhimurium Infection
Publikation
Damigos S,
Caliskan A,
Wajant G,
Giddins S,
Moldovan A,
Kuhn S,
Putz E,
Dandekar T,
Rudel T,
Westermann AJ,
Zdzieblo D
(2025)
Advanced Science, 12, 9, e2411233, 10.1002/advs.202411233, 39807570
Advanced Science, 12, 9, e2411233, 10.1002/advs.202411233, 39807570
Meeting report ASOBIOTICS 2024: an interdisciplinary symposium on antisense-based programmable RNA antibiotics
Publikation
Vogel J,
Faber F,
Barquist L,
Sparmann A,
Popella L,
Ghosh C
(2025)
RNA, 31, 4, 465-474, 10.1261/rna.080347.124, 39814459
RNA, 31, 4, 465-474, 10.1261/rna.080347.124, 39814459
High-Throughput Tiling of Essential mRNAs Increases Potency of Antisense Antibiotics
Publikation
Danti G,
Popella L,
Vogel J,
Maric HM
(2025)
Advanced Science, (Online ahead of print), e2504284, 10.1002/advs.202504284, 40304263
Advanced Science, (Online ahead of print), e2504284, 10.1002/advs.202504284, 40304263
AcrVIB1 inhibits CRISPR-Cas13b immunity by promoting unproductive crRNA binding accessible to RNase attack
Publikation
Wandera KG,
Schmelz S,
Migur A,
Kibe A,
Lukat P,
Achmedov T,
Caliskan N,
Blankenfeldt W,
Beisel CL
(2025)
Molecular Cell, 85, 6, 1162-1175, 10.1016/j.molcel.2025.01.020, 39965569
Molecular Cell, 85, 6, 1162-1175, 10.1016/j.molcel.2025.01.020, 39965569
Demultiplexing and barcode-specific adaptive sampling for nanopore direct RNA sequencing
Publikation
van der Toorn W,
Bohn P,
Liu-Wei W,
Olguin-Nava M,
Gribling-Burrer AS,
Smyth RP,
von Kleist M
(2025)
Nature Communications, 16, 1, 3742, 10.1038/s41467-025-59102-9, 40258808
Nature Communications, 16, 1, 3742, 10.1038/s41467-025-59102-9, 40258808
Guidelines for minimal reporting requirements, design and interpretation of experiments involving the use of eukaryotic dual gene expression reporters (MINDR)
Publikation
Loughran G,
Andreev DE,
Terenin IM,
Namy O,
Mikl M,
Yordanova MM,
McManus CJ,
Firth AE,
Atkins JF,
Fraser CS,
Ignatova Z,
Iwasaki S,
Kufel J,
Larsson O,
Leidel SA,
Mankin AS,
Mariotti M,
Tanenbaum ME,
Topisirovic I,
Vázquez-Laslop N,
Viero G,
Caliskan N,
Chen Y,
Clark PL,
Dinman JD,
Farabaugh PJ,
Gilbert WV,
Ivanov P,
Kieft JS,
Mühlemann O,
Sachs MS,
Shatsky IN,
Sonenberg N,
Steckelberg AL,
Willis AE,
Woodside MT,
Valasek LS,
Dmitriev SE,
Baranov PV
(2025)
Nature Structural & Molecular Biology, 32, 3, 418-430, 10.1038/s41594-025-01492-x, 40033152
Nature Structural & Molecular Biology, 32, 3, 418-430, 10.1038/s41594-025-01492-x, 40033152
Optimization of Structure-Guided Development of Chemical Probes for the Pseudoknot RNA of the Frameshift Element in SARS-CoV-2
Publikation
Ceylan B,
Adam J,
Toews S,
Kaiser F,
Dörr J,
Scheppa D,
Tants JN,
Smart A,
Schoth J,
Philipp S,
Stirnal E,
Ferner J,
Richter C,
Sreeramulu S,
Caliskan N,
Schlundt A,
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Göbel M,
Wacker A,
Schwalbe H
(2025)
Angewandte Chemie International Edition, 64, 9, e202417961, 10.1002/anie.202417961, 39887818
Angewandte Chemie International Edition, 64, 9, e202417961, 10.1002/anie.202417961, 39887818
Streamlined and efficient genome editing in Cupriavidus necator H16 using an optimised SIBR-Cas system
Publikation
Della Valle S,
Orsi E,
Creutzburg SCA,
Jansen LFM,
Pentari EN,
Beisel CL,
Steel H,
Nikel PI,
Staals RHJ,
Claassens NJ,
van der Oost J,
Huang WE,
Patinios C
(2025)
Trends in Biotechnology, 43, 6, 1470-1491, 10.1016/j.tibtech.2025.02.006, 40087133
Trends in Biotechnology, 43, 6, 1470-1491, 10.1016/j.tibtech.2025.02.006, 40087133