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A scalable gut epithelial organoid model reveals the genome-wide colonization landscape of a human-adapted pathogen

Publikation
Di Martino ML, Jenniches L, Bhetwal A, Eriksson J, Lopes ACC, Ntokaki A, Pasqua M, Sundbom M, Skogar M, Graf W, Webb DL, Hellström PM, Mateus A, Barquist L, Sellin ME (2025)
Nature Genetics, 57, 7, 1730-1741, 10.1038/s41588-025-02218-x, 40506541

Meeting report ASOBIOTICS 2024: an interdisciplinary symposium on antisense-based programmable RNA antibiotics

Publikation
Vogel J, Faber F, Barquist L, Sparmann A, Popella L, Ghosh C (2025)
RNA, 31, 4, 465-474, 10.1261/rna.080347.124, 39814459

High-Throughput Tiling of Essential mRNAs Increases Potency of Antisense Antibiotics

Publikation
Danti G, Popella L, Vogel J, Maric HM (2025)
Advanced Science, (Online ahead of print), e2504284, 10.1002/advs.202504284, 40304263

AcrVIB1 inhibits CRISPR-Cas13b immunity by promoting unproductive crRNA binding accessible to RNase attack

Publikation
Wandera KG, Schmelz S, Migur A, Kibe A, Lukat P, Achmedov T, Caliskan N, Blankenfeldt W, Beisel CL (2025)
Molecular Cell, 85, 6, 1162-1175, 10.1016/j.molcel.2025.01.020, 39965569

Fusobacterium nucleatum interacts with cancer-associated fibroblasts to promote colorectal cancer

Publikation
Karta J, Meyers M, Rodriguez F, Koncina E, Gilson C, Klein E, Gabola M, Benzarti M, Pérez Escriva P, Molina Tijeras JA, Correia Tavares Bernardino C, Ponath F, Carpentier A, Pujabet MA, Schmoetten M, Tsenkova M, Saoud P, Gaigneaux A, Ternes D, Alonso L, Zügel N, Willemssen E, Koppes P, Léonard D, Casanova LP, Haan S, Mittelbronn M, Meiser J, Pozdeev VI, Vogel J, Nuciforo PG, Wilmes P, Letellier E (2025)
The EMBO Journal, online ahead of print, 10.1038/s44318-025-00542-w, 40846900

Hepatitis C virus NS3 helicase contributes to (-) strand RNA synthesis

Publikation
Ralfs P, Bressanelli S, Günter LM, Gabel A, Rothhaar P, Price KJ, Tubiana T, Munschauer M, Frick DN, Lohmann V (2025)
Nature Communications, 16, 1, 8006, 10.1038/s41467-025-63498-9, 40866424

Demultiplexing and barcode-specific adaptive sampling for nanopore direct RNA sequencing

Publikation
van der Toorn W, Bohn P, Liu-Wei W, Olguin-Nava M, Gribling-Burrer AS, Smyth RP, von Kleist M (2025)
Nature Communications, 16, 1, 3742, 10.1038/s41467-025-59102-9, 40258808

Guidelines for minimal reporting requirements, design and interpretation of experiments involving the use of eukaryotic dual gene expression reporters (MINDR)

Publikation
Loughran G, Andreev DE, Terenin IM, Namy O, Mikl M, Yordanova MM, McManus CJ, Firth AE, Atkins JF, Fraser CS, Ignatova Z, Iwasaki S, Kufel J, Larsson O, Leidel SA, Mankin AS, Mariotti M, Tanenbaum ME, Topisirovic I, Vázquez-Laslop N, Viero G, Caliskan N, Chen Y, Clark PL, Dinman JD, Farabaugh PJ, Gilbert WV, Ivanov P, Kieft JS, Mühlemann O, Sachs MS, Shatsky IN, Sonenberg N, Steckelberg AL, Willis AE, Woodside MT, Valasek LS, Dmitriev SE, Baranov PV (2025)
Nature Structural & Molecular Biology, 32, 3, 418-430, 10.1038/s41594-025-01492-x, 40033152

Optimization of Structure-Guided Development of Chemical Probes for the Pseudoknot RNA of the Frameshift Element in SARS-CoV-2

Publikation
Ceylan B, Adam J, Toews S, Kaiser F, Dörr J, Scheppa D, Tants JN, Smart A, Schoth J, Philipp S, Stirnal E, Ferner J, Richter C, Sreeramulu S, Caliskan N, Schlundt A, Weigand JE, Göbel M, Wacker A, Schwalbe H (2025)
Angewandte Chemie International Edition, 64, 9, e202417961, 10.1002/anie.202417961, 39887818

Streamlined and efficient genome editing in Cupriavidus necator H16 using an optimised SIBR-Cas system

Publikation
Della Valle S, Orsi E, Creutzburg SCA, Jansen LFM, Pentari EN, Beisel CL, Steel H, Nikel PI, Staals RHJ, Claassens NJ, van der Oost J, Huang WE, Patinios C (2025)
Trends in Biotechnology, 43, 6, 1470-1491, 10.1016/j.tibtech.2025.02.006, 40087133