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Pan-modification profiling facilitates a cross-evolutionary dissection of the thermoregulated ribosomal epitranscriptome
Publikation
Garcia-Campos MA,
Georgeson J,
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Fluke KA,
Matzov D,
Iyer V,
Burkhart BW,
Lui L,
Kustanovich A,
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Howpay-Manage SA,
Gerovac M,
Alexandre N,
Nobe Y,
Nowak JS,
Perera M,
Apostle A,
Fang S,
Glatt S,
Jona G,
Ferreira-Cerca S,
Vogel J,
Taoka M,
Meier JL,
Westhof E,
Santangelo TJ,
Grohmann D,
Shalev-Benami M,
Schwartz S,
Garcia-Campos MA,
Georgeson J,
Nir R,
Reichelt R,
Fluke KA,
Matzov D,
Iyer V,
Burkhart BW,
Lui L,
Kustanovich A,
Grünberger F,
Thalalla-Gamage S,
Howpay-Manage SA,
Gerovac M,
Alexandre N,
Nobe Y,
Nowak JS,
Perera M,
Apostle A,
Fang S,
Glatt S,
Jona G,
Ferreira-Cerca S,
Vogel J,
Taoka M,
Meier JL,
Westhof E,
Santangelo TJ,
Grohmann D,
Shalev-Benami M,
Schwartz S
(2025)
Cell, 188, 24, 6825-6844.e28, 10.1016/j.cell.2025.09.014, 41130207
Cell, 188, 24, 6825-6844.e28, 10.1016/j.cell.2025.09.014, 41130207
A resurrected ancestor of Cas12a expands target access and substrate recognition for nucleic acid editing and detection
Publikation
Jabalera Y,
Tascón I,
Samperio S,
López-Alonso JP,
Gonzalez-Lopez M,
Aransay AM,
Abascal-Palacios G,
Beisel CL,
Ubarretxena-Belandia I,
Perez-Jimenez R
(2025)
Nature Biotechnology, 43, 10, 1663-1672, 10.1038/s41587-024-02461-3, 39482449
Nature Biotechnology, 43, 10, 1663-1672, 10.1038/s41587-024-02461-3, 39482449
Disparate mechanisms counteract extraneous CRISPR RNA production in type II-C CRISPR-Cas systems
Publikation
Feussner M,
Migur A,
Mitrofanov A,
Alkhnbashi OS,
Backofen R,
Beisel CL,
Weinberg Z
(2025)
microLife, 6, uqaf007, 10.1093/femsml/uqaf007, 40376300
microLife, 6, uqaf007, 10.1093/femsml/uqaf007, 40376300
A Multicellular In Vitro Model of the Human Intestine with Immunocompetent Features Highlights Host-Pathogen Interactions During Early Salmonella Typhimurium Infection
Publikation
Damigos S,
Caliskan A,
Wajant G,
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Moldovan A,
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(2025)
Advanced Science, 12, 9, e2411233, 10.1002/advs.202411233, 39807570
Advanced Science, 12, 9, e2411233, 10.1002/advs.202411233, 39807570
Proton-pump inhibitors increase C. difficile infection risk by altering pH rather than by affecting the gut microbiome based on a bioreactor model
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Schumacher J,
Müller P,
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Faber F,
Molitor B,
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(2025)
Gut Microbes, 17, 1, 2519697, 10.1080/19490976.2025.2519697, 40524314
Gut Microbes, 17, 1, 2519697, 10.1080/19490976.2025.2519697, 40524314
Allogeneic hematopoietic cell transplantation initiates atherosclerosis in mice via CD8+ T cells // Allogeneic haematopoietic cell transplantation promotes atherosclerosis in mice via CD8+ T cells
Publikation
Jorgacevic I,
Shaikh H,
Ali H,
Bundalo M,
Schäfer S,
Kern MAG,
Büttner-Herold M,
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(2025)
Cardiovascular Research, 121, 17, 2668-2678, 10.1093/cvr/cvaf229, 41252283
Cardiovascular Research, 121, 17, 2668-2678, 10.1093/cvr/cvaf229, 41252283
High-Fidelity and Cost-Effective Engineering of SARS-CoV-2
Publikation
Olguin-Nava M,
Hennig T,
Börtlein C,
Bohn P,
Ambi UB,
Gabel A,
Günter LM,
Gribling-Burrer AS,
Schmidt N,
Caliskan N,
Dölken L,
Munschauer M,
Smyth RP
(2025)
Viruses, 17, 12, 1604, 10.3390/v17121604, 41472274
Viruses, 17, 12, 1604, 10.3390/v17121604, 41472274
A scalable gut epithelial organoid model reveals the genome-wide colonization landscape of a human-adapted pathogen
Publikation
Di Martino ML,
Jenniches L,
Bhetwal A,
Eriksson J,
Lopes ACC,
Ntokaki A,
Pasqua M,
Sundbom M,
Skogar M,
Graf W,
Webb DL,
Hellström PM,
Mateus A,
Barquist L,
Sellin ME
(2025)
Nature Genetics, 57, 7, 1730-1741, 10.1038/s41588-025-02218-x, 40506541
Nature Genetics, 57, 7, 1730-1741, 10.1038/s41588-025-02218-x, 40506541
Meeting report ASOBIOTICS 2024: an interdisciplinary symposium on antisense-based programmable RNA antibiotics
Publikation
Vogel J,
Faber F,
Barquist L,
Sparmann A,
Popella L,
Ghosh C
(2025)
RNA, 31, 4, 465-474, 10.1261/rna.080347.124, 39814459
RNA, 31, 4, 465-474, 10.1261/rna.080347.124, 39814459
High-Throughput Tiling of Essential mRNAs Increases Potency of Antisense Antibiotics
Publikation
Danti G,
Popella L,
Vogel J,
Maric HM
(2025)
Advanced Science, 12, 28, e2504284, 10.1002/advs.202504284, 40304263
Advanced Science, 12, 28, e2504284, 10.1002/advs.202504284, 40304263