Suche
Deciphering Polymer Interactions in Bioconjugates with Different Architectures by Structural Analysis via Time-Resolved Limited Proteolysis Mass Spectrometry
Publikation
Hamm P,
Driessen MD,
Hauptstein N,
Kehrein J,
Worschech R,
Pouyan P,
Haag R,
Schubert US,
Müller TD,
Meinel L,
Lühmann T
(2025)
Angewandte Chemie - International Edition, 64, 9, e202415354, 10.1002/anie.202415354, 39780761
Angewandte Chemie - International Edition, 64, 9, e202415354, 10.1002/anie.202415354, 39780761
Targeted DNA ADP-ribosylation triggers templated repair in bacteria and base mutagenesis in eukaryotes
Publikation
Gupta D,
Patinios C,
Bassett HV,
Kibe A,
Collins SP,
Kamm C,
Wang Y,
Zhao C,
Vollen K,
Toussaint C,
Calvin I,
Cullot G,
Aird EJ,
Polkoff KM,
Nguyen-Vo TP,
Migur A,
Schut F,
Al'Abri IS,
Achmedov T,
Del Re A,
Corn JE,
Saliba AE,
Crook N,
Stepanova AN,
Alonso JM,
Beisel CL,
Patinios C,
Gupta D,
Bassett HV,
Collins SP,
Kamm C,
Kibe A,
Wang Y,
Zhao C,
Vollen K,
Toussaint C,
Polkoff KM,
Nguyen T,
Calvin I,
Migur A,
Al'Abri IS,
Achmedov T,
Del Re A,
Saliba A,
Crook N,
Stepanova AN,
Alonso JM,
Beisel CL,
Cullot G,
Aird EJ,
Nguyen-Vo TP,
Schut F,
Corn JE
(2025)
Nature Biotechnology, (Online ahead of print), 10.1038/s41587-025-02802-w, 40908325
Nature Biotechnology, (Online ahead of print), 10.1038/s41587-025-02802-w, 40908325
Impurity profiling of PEGylated myristoyl diglyceride, DMG-PEG 2000, a functional excipient used in mRNA lipid nanoparticle formulations
Publikation
Sperber B,
Gutmann M,
Kehrein J,
Lühmann T,
Holzgrabe U,
Meinel L
(2025)
European Journal of Pharmaceutics and Biopharmaceutics, 214, 114762, 10.1016/j.ejpb.2025.114762, 40480444
European Journal of Pharmaceutics and Biopharmaceutics, 214, 114762, 10.1016/j.ejpb.2025.114762, 40480444
An updated evolutionary classification of CRISPR-Cas systems including rare variants
Publikation
Makarova KS,
Shmakov SA,
Wolf YI,
Mutz P,
Altae-Tran H,
Beisel CL,
Brouns SJJ,
Charpentier E,
Cheng D,
Doudna J,
Haft DH,
Horvath P,
Moineau S,
Mojica FJM,
Pausch P,
Pinilla-Redondo R,
Shah SA,
Siksnys V,
Terns MP,
Tordoff J,
Venclovas C,
White MF,
Yakunin AF,
Zhang F,
Garrett RA,
Backofen R,
van der Oost J,
Barrangou R,
Koonin EV,
Makarova KS,
Shmakov SA,
Wolf YI,
Mutz P,
Altae-Tran H,
Beisel CL,
Brouns SJ,
Charpentier E,
Cheng D,
Doudna J,
Haft DH,
Horvath P,
Moineau S,
Mojica FJ,
Pausch P,
Pinilla-Redondo R,
Shah SA,
Siksnys V,
Terns MP,
Tordoff J,
Venclovas C,
White MF,
Yakunin AF,
Zhang F,
Garrett RA,
Backofen R,
van der Oost J,
Barrangou R,
Koonin EV
(2025)
Nature Microbiology, 10, 12, 3346-3361, 10.1038/s41564-025-02180-8, 41198952
Nature Microbiology, 10, 12, 3346-3361, 10.1038/s41564-025-02180-8, 41198952
Functional characterization of the DUF1127-containing small protein YjiS of Salmonella Typhimurium
Publikation
Venturini E,
Maaß S,
Bischler T,
Becher D,
Vogel J,
Westermann AJ
(2025)
microLife, 6, uqae026, 10.1093/femsml/uqae026, 39790481
microLife, 6, uqae026, 10.1093/femsml/uqae026, 39790481
Programmable antisense oligomers for phage functional genomics
Publikation
Gerovac M,
Buhlmann L,
Zhu Y,
Ðurica-Mitic S,
Rech V,
Carien S,
Gräfenhan T,
Popella L,
Vogel J,
Gerovac M,
Buhlmann L,
Zhu Y,
Ðurica-Mitic S,
Rech V,
Carien S,
Gräfenhan T,
Popella L,
Vogel J
(2025)
Nature, 646, 8087, 1195-1203, 10.1038/s41586-025-09499-6, 40931073
Nature, 646, 8087, 1195-1203, 10.1038/s41586-025-09499-6, 40931073
Unveiling immune interference: how the dendritic cell response to co-infection with Aspergillus fumigatus is modulated by human cytomegalovirus and its virokine CMVIL-10
Publikation
Heilig L,
Bussemer L,
Strobel L,
Hünniger-Ast K,
Kurzai O,
Grothey A,
Dölken L,
Laib Sampaio K,
Panagiotou G,
Westermann AJ,
Einsele H,
Wurster S,
Schäuble S,
Löffler J,
Heilig L,
Bussemer L,
Strobel L,
Hünniger-Ast K,
Kurzai O,
Grothey A,
Dölken L,
Laib Sampaio K,
Panagiotou G,
Westermann AJ,
Einsele H,
Wurster S,
Schäuble S,
Löffler J
(2025)
mBio, 16, 11, 10.1128/mbio.01541-25, 40980889
mBio, 16, 11, 10.1128/mbio.01541-25, 40980889
An sRNA overexpression library reveals AbnZ as a negative regulator of an essential translocation module in Caulobacter crescentus
Publikation
Velasco-Gomariz M,
Sulzer J,
Faber F,
Fröhlich KS
(2025)
Nucleic Acids Research, 53, 1, gkae1139, 10.1093/nar/gkae1139, 39657128
Nucleic Acids Research, 53, 1, gkae1139, 10.1093/nar/gkae1139, 39657128
Intramacrophage RIL-seq uncovers an RNA antagonist of the Salmonella virulence-associated small RNA PinT
Publikation
Kooshapour H,
Matera G,
Venturini E,
Metka L,
Bischler T,
Vogel J,
Westermann AJ
(2025)
Nucleic Acids Research, 53, 22, gkaf1364, 10.1093/nar/gkaf1364, 41428736
Nucleic Acids Research, 53, 22, gkaf1364, 10.1093/nar/gkaf1364, 41428736
Meeting report 'Microbiology 2023: from single cell to microbiome and host', an international interacademy conference in Würzburg
Publikation
Cossart P,
Hacker J,
Holden DH,
Normark S,
Vogel J
(2024)
microLife, 5, uqae008, 10.1093/femsml/uqae008, 38665235
microLife, 5, uqae008, 10.1093/femsml/uqae008, 38665235