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Lab-scale siRNA and mRNA LNP manufacturing by various microfluidic mixing techniques – an evaluation of particle properties and efficiency
Publikation
Jürgens DC,
Deßloch L,
Porras-Gonzalez D,
Winkeljann J,
Zielinski S,
Munschauer M,
Hörner AL,
Burgstaller G,
Winkeljann B,
Merkel OM
(2023)
OpenNano, 12, 1, 100161, 10.1016/j.onano.2023.100161
OpenNano, 12, 1, 100161, 10.1016/j.onano.2023.100161
Sequential disruption of SPLASH-identified vRNA-vRNA interactions challenges their role in influenza A virus genome packaging
Publikation
Jakob C,
Lovate GL,
Desirò D,
Gießler L,
Smyth RP,
Marquet R,
Lamkiewicz K,
Marz M,
Schwemmle M,
Bolte H
(2023)
Nucleic Acids Research, 51, 12, 6479-6494, 10.1093/nar/gkad442, 37224537
Nucleic Acids Research, 51, 12, 6479-6494, 10.1093/nar/gkad442, 37224537
Grad-seq analysis of Enterococcus faecalis and Enterococcus faecium provides a global view of RNA and protein complexes in these two opportunistic pathogens
Publikation
Michaux C,
Gerovac M,
Hansen EE,
Barquist L,
Vogel J
(2023)
microLife, 4, uqac027, 10.1093/femsml/uqac027, 37223738
microLife, 4, uqac027, 10.1093/femsml/uqac027, 37223738
Design and off-target prediction for antisense oligomers targeting bacterial mRNAs with the MASON webserver
Publikation
Jung JJ,
Popella L,
Do PT,
Pfau P,
Vogel J,
Barquist L
(2023)
RNA, 299, 5, 570-583, 10.1261/rna.079263.122, 36750372
RNA, 299, 5, 570-583, 10.1261/rna.079263.122, 36750372
RNA targeting unleashes indiscriminate nuclease activity of CRISPR-Cas12a2
Publikation
Bravo JPK,
Hallmark T,
Naegle B,
Beisel CL,
Jackson RN,
Taylor DW
(2023)
Nature, 613, 7944, 582-587, 10.1038/s41586-022-05560-w, 36599980
Nature, 613, 7944, 582-587, 10.1038/s41586-022-05560-w, 36599980
Advancing massive transcriptional profiling of single bacteria
Publikation
Saliba AE
(2023)
Cell Reports Methods, 3, 2, 100416, 10.1016/j.crmeth.2023.100416, 36936081
Cell Reports Methods, 3, 2, 100416, 10.1016/j.crmeth.2023.100416, 36936081
Altered and allele-specific open chromatin landscape reveals epigenetic and genetic regulators of innate immunity in COVID-19
Publikation
Zhang B,
Zhang Z,
Koeken VACM,
Kumar S,
Aillaud M,
Tsay HC,
Liu Z,
Kraft ARM,
Soon CF,
Odak I,
Bošnjak B,
Vlot A,
Deutsche COVID-19 OMICS Initiative,
Swertz MA,
Ohler U,
Geffers R,
Illig T,
Huehn J,
Saliba AE,
Sander LE,
Förster R,
Xu CJ,
Cornberg M,
Schulte LN,
Li Y
(2023)
Cell Genomics, 3, 2, 100232, 10.1016/j.xgen.2022.100232, 36474914
Cell Genomics, 3, 2, 100232, 10.1016/j.xgen.2022.100232, 36474914
Central Role of Sibling Small RNAs NgncR_162 and NgncR_163 in Main Metabolic Pathways of Neisseria gonorrhoeae
Publikation
Steiner T,
Zachary M,
Bauer S,
Müller MJ,
Krischke M,
Radziej S,
Klepsch M,
Huettel B,
Eisenreich W,
Rudel T,
Beier D
(2023)
mBio, 14, 1, 10.1128/mbio.03093-22, 36598194
mBio, 14, 1, 10.1128/mbio.03093-22, 36598194
DOT1L activity affects neural stem cell division mode and reduces differentiation and ASNS expression
Publikation
Appiah B,
Fullio CL,
Ossola C,
Bertani I,
Restelli E,
Cheffer A,
Polenghi M,
Haffner C,
Garcia-Miralles M,
Zeis P,
Treppner M,
Bovio P,
Schlichtholz L,
Mas-Sanchez A,
Zografidou L,
Winter J,
Binder H,
Grün D,
Kalebic N,
Taverna E,
Vogel T
(2023)
EMBO Reports, 24, 8, e56233, 10.15252/embr.202256233, 37382163
EMBO Reports, 24, 8, e56233, 10.15252/embr.202256233, 37382163
Integrated single-cell analysis based classification of vascular mononuclear phagocytes in mouse and human atherosclerosis
Publikation
Zernecke A,
Erhard F,
Weinberger T,
Schulz C,
Ley K,
Saliba AE,
Cochain C
(2023)
Cardiovascular Research, 119, 8, 1676-1689, 10.1093/cvr/cvac161, 36190844
Cardiovascular Research, 119, 8, 1676-1689, 10.1093/cvr/cvac161, 36190844