Suche
A target expression threshold dictates invader defense and prevents autoimmunity by CRISPR-Cas13
Publikation
Vialetto E,
Yu Y,
Collins SP,
Wandera KG,
Barquist L,
Beisel CL
(2022)
Cell Host & Microbe, 3128, 22, 00273-6, 10.1016/j.chom.2022.05.013, 35690065
Cell Host & Microbe, 3128, 22, 00273-6, 10.1016/j.chom.2022.05.013, 35690065
Differentially Optimized Cell-Free Buffer Enables Robust Expression from Unprotected Linear DNA in Exonuclease-Deficient Extracts
Publikation
Batista AC,
Levrier A,
Soudier P,
Voyvodic PL,
Achmedov T,
Reif-Trauttmansdorff T,
DeVisch A,
Cohen-Gonsaud M,
Faulon JL,
Beisel CL,
Bonnet J,
Kushwaha M
(2022)
ACS Synthetic Biology, 11, 2, 732-746, 10.1021/acssynbio.1c00448, 35034449
ACS Synthetic Biology, 11, 2, 732-746, 10.1021/acssynbio.1c00448, 35034449
PEtOxylated Interferon-α2a Bioconjugates Addressing H1N1 Influenza A Virus Infection
Publikation
Hauptstein N,
Dirauf M,
Wittwer K,
Cinar G,
Siering O,
Raschig M,
Lühmann T,
Scherf-Clavel O,
Sawatsky B,
Nischang I,
Schubert US,
Pfaller CK,
Meinel L
(2022)
Biomacromolecules, 23, 9, 3593–3601, 10.1021/acs.biomac.2c00358, 35904477
Biomacromolecules, 23, 9, 3593–3601, 10.1021/acs.biomac.2c00358, 35904477
Rapid cell-free characterization of multi-subunit CRISPR effectors and transposons
Publikation
Wimmer F,
Mougiakos I,
Englert F,
Beisel CL
(2022)
Molecular Cell, 82, 6, 1210-1224.e6, 10.1016/j.molcel.2022.01.026, 35216669
Molecular Cell, 82, 6, 1210-1224.e6, 10.1016/j.molcel.2022.01.026, 35216669
Comprehensive analysis of PNA-based antisense antibiotics targeting various essential genes in uropathogenic Escherichia coli
Publikation
Popella L,
Jung J,
Do PT,
Hayward RJ,
Barquist L,
Vogel J
(2022)
Nucleic Acids Research, 50, 11, 6435–6452, 10.1093/nar/gkac362, 35687096
Nucleic Acids Research, 50, 11, 6435–6452, 10.1093/nar/gkac362, 35687096
Cellular RNA Targets of Cold Shock Proteins CspC and CspE and Their Importance for Serum Resistance in Septicemic Escherichia coli
Publikation
Yair Y,
Michaux C,
Biran D,
Bernhard J,
Vogel J,
Barquist L,
Ron EZ
(2022)
mSystems, 7, 4, e0008622, 10.1128/msystems.00086-22, 35695420
mSystems, 7, 4, e0008622, 10.1128/msystems.00086-22, 35695420
An expanded arsenal of immune systems that protect bacteria from phages
Publikation
Millman A,
Melamed S,
Leavitt A,
Doron S,
Bernheim A,
Hör J,
Garb J,
Bechon N,
Brandis A,
Lopatina A,
Ofir G,
Hochhauser D,
Stokar-Avihail A,
Tal N,
Sharir S,
Voichek M,
Erez Z,
Ferrer JLM,
Dar D,
Kacen A,
Amitai G,
Sorek R
(2022)
Cell Host & Microbe, 30, 11, 1556-1569.e5, 10.1016/j.chom.2022.09.017, 36302390
Cell Host & Microbe, 30, 11, 1556-1569.e5, 10.1016/j.chom.2022.09.017, 36302390
Stage-specific and cell type-specific requirements of ikzf1 during haematopoietic differentiation in zebrafish
Publikation
Hess I,
Sagar,
O Meara C,
Grün D,
Schorpp M,
Boehm T
(2022)
Scientific Reports, 12, 1, 21401, 10.1038/s41598-022-25978-6, 36496511
Scientific Reports, 12, 1, 21401, 10.1038/s41598-022-25978-6, 36496511
Lymphatic migration of unconventional T cells promotes site-specific immunity in distinct lymph nodes
Publikation
Ataide MA,
Knöpper K,
Cruz de Casas P,
Ugur M,
Eickhoff S,
Zou M,
Shaikh H,
Trivedi A,
Grafen A,
Yang T,
Prinz I,
Ohlsen K,
Gomez de Agüero M,
Beilhack A,
Huehn J,
Gaya M,
Saliba AE,
Gasteiger G,
Kastenmüller W
(2022)
Immunity, 55, 10, 1813–1828.e9, 10.1016/j.immuni.2022.07.019, 36002023
Immunity, 55, 10, 1813–1828.e9, 10.1016/j.immuni.2022.07.019, 36002023
The DNA polymerase of bacteriophage YerA41 replicates its T-modified DNA in a primer-independent manner
Publikation
Gomez-Raya-Vilanova MV,
Leskinen K,
Bhattacharjee A,
Virta P,
Rosenqvist P,
Smith JLR,
Bayfield OW,
Homberger C,
Kerrinnes T,
Vogel J,
Pajunen MI,
Skurnik M
(2022)
Nucleic Acids Research, 50, 7, 3985-3997, 10.1093/nar/gkac203, 35357498
Nucleic Acids Research, 50, 7, 3985-3997, 10.1093/nar/gkac203, 35357498