Suche
Improved prediction of bacterial CRISPRi guide efficiency from depletion screens through mixed-effect machine learning and data integration
Publikation
Yu Y,
Gawlitt S,
de Andrade E Sousa LB,
Merdivan E,
Piraud M,
Beisel CL,
Barquist L
(2024)
Genome Biology, 25, 1, 13, 10.1186/s13059-023-03153-y, 38200565
Genome Biology, 25, 1, 13, 10.1186/s13059-023-03153-y, 38200565
Streptococcus agalactiae strain COH1 transcriptome in association with stem cell-derived brain-like endothelial cells
Publikation
Vollmuth N,
Sauerwein T,
Foerstner KU,
Westermann AJ,
Schubert-Unkmeir A,
Lam DW,
Kim BJ
(2024)
Microbiology Resource Announcements, 13, 12, e00455-24, 10.1128/mra.00455-24, 39526785
Microbiology Resource Announcements, 13, 12, e00455-24, 10.1128/mra.00455-24, 39526785
The conserved noncoding RNA ModT coordinates growth and virulence in Clostridioides difficile
Publikation
Lence T,
Sulzer J,
Andress K,
Gribling-Burrer AS,
Lamm-Schmidt V,
Barquist L,
Smyth RP,
Faber F
(2024)
PLOS Biology, 22, 12, e3002948, 10.1371/journal.pbio.3002948, 39671441
PLOS Biology, 22, 12, e3002948, 10.1371/journal.pbio.3002948, 39671441
Recruitment of multi-segment genomic RNAs by Bluetongue virus requires a preformed RNA network
Publikation
Sung PY,
Phelan JE,
Luo D,
Kulasegaran-Shylini R,
Bohn P,
Smyth RP,
Roy P (2024)P.,
Roy P
(2024)
Nucleic Acids Research, 52, 14, 8500-8514, 10.1093/nar/gkae404, 38769067
Nucleic Acids Research, 52, 14, 8500-8514, 10.1093/nar/gkae404, 38769067
The life-saving benefit of dexamethasone in severe COVID-19 is linked to a reversal of monocyte dysregulation
Publikation
Knoll R,
Helbig ET,
Dahm K,
Bolaji O,
Hamm F,
Dietrich O,
van Uelft M,
Müller S,
Bonaguro L,
Schulte-Schrepping J,
Petrov L,
Krämer B,
Kraut M,
Stubbemann P,
Thibeault C,
Brumhard S,
Theis H,
Hack G,
Domenico E,
Nattermann J,
Becker M,
Beyer MD,
Hillus D,
Georg P,
Loers C,
Tiedemann J,
Tober-Lau P,
Lippert L,
Millet PLB,
Tacke F,
Rohde G,
Suttorp N,
Witzenrath M,
Saliba AE,
Ulas T,
Polansky JK,
Sawitzki B,
Sander LE,
Schultze JL,
Aschenbrenner AC,
Kurth F
(2024)
Cell, 187, 16, 4318-4335.e20, 10.1016/j.cell.2024.06.014, 38964327
Cell, 187, 16, 4318-4335.e20, 10.1016/j.cell.2024.06.014, 38964327
An expanded transcriptome atlas for Bacteroides thetaiotaomicron reveals a small RNA that modulates tetracycline sensitivity
Publikation
Ryan D,
Bornet E,
Prezza G,
Alampalli SV,
Franco de Carvalho T,
Felchle H,
Ebbecke T,
Hayward RJ,
Deutschbauer AM,
Barquist L,
Westermann AJ
(2024)
Nature Microbiology, 9, 4, 1130-1144, 10.1038/s41564-024-01642-9, 38528147
Nature Microbiology, 9, 4, 1130-1144, 10.1038/s41564-024-01642-9, 38528147
Decoding spatiotemporal transcriptional dynamics and epithelial fibroblast crosstalk during gastroesophageal junction development through single cell analysis
Publikation
Kumar N,
Prakash PG,
Wentland C,
Kurian SM,
Jethva G,
Brinkmann V,
Mollenkopf HJ,
Krammer T,
Toussaint C,
Saliba AE,
Biebl M,
Jürgensen C,
Wiedenmann B,
Meyer TF,
Gurumurthy RK,
Chumduri C
(2024)
Nature Communications, 15, 1, 3064, 10.1038/s41467-024-47173-z, 38594232
Nature Communications, 15, 1, 3064, 10.1038/s41467-024-47173-z, 38594232
Spatial transcriptomics reveals profound subclonal heterogeneity and T-cell dysfunction in extramedullary myeloma
Publikation
John M,
Helal M,
Duell J,
Mattavelli G,
Stanojkovska E,
Afrin N,
Leipold AM,
Steinhardt MJ,
Zhou X,
Žihala D,
Anilkumar Sithara A,
Mersi J,
Waldschmidt JM,
Riedhammer C,
Kadel SK,
Truger M,
Werner RA,
Haferlach C,
Einsele H,
Kretzschmar K,
Jelínek T,
Rosenwald A,
Kortüm KM,
Riedel A,
Rasche L
(2024)
Blood, 144, 20, 2121-2135, 10.1182/blood.2024024590, 39172759
Blood, 144, 20, 2121-2135, 10.1182/blood.2024024590, 39172759
A method to correct for local alterations in DNA copy number that bias functional genomics assays applied to antibiotic-treated bacteria
Publikation
Sullivan GJ,
Barquist L,
Cain AK
(2024)
mSystems, 12, e0066523, 10.1128/msystems.00665-23, 38470252
mSystems, 12, e0066523, 10.1128/msystems.00665-23, 38470252
Refining the transcriptional landscapes for distinct clades of virulent phages infecting Pseudomonas aeruginosa
Publikation
Putzeys L,
Wicke L,
Boon M,
van Noort V,
Vogel J,
Lavigne R
(2024)
microLife, 5, uqae002, 10.1093/femsml/uqae002, 38444699
microLife, 5, uqae002, 10.1093/femsml/uqae002, 38444699