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tRNA as an assembly chaperone for a macromolecular transcription-processing complex
Publikation
Bartuli J,
Jungwirth S,
Dixit M,
Okuda T,
Zimmermann JP,
Erlacher M,
Pan T,
Volz A,
Hüttenhofer A,
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Fischer U,
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Zimmermann JP,
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Pan T,
Volz A,
Hüttenhofer A,
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Höbartner C,
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(2025)
Nature Structural & Molecular Biology, 32, 11, 2349-2358, 10.1038/s41594-025-01653-y, 40908366
Nature Structural & Molecular Biology, 32, 11, 2349-2358, 10.1038/s41594-025-01653-y, 40908366
Designing the Aplysia punctata Arginine-Depleting Enzyme for Tumor Targeting
Publikation
Wolkersdorfer AM,
Endo Y,
Kehrein J,
Kappus M,
Hattori S,
Gutmann M,
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(2025)
Molecular Pharmaceutics, 22, 3, 1253–1261, 10.1021/acs.molpharmaceut.4c00964, 39950605
Molecular Pharmaceutics, 22, 3, 1253–1261, 10.1021/acs.molpharmaceut.4c00964, 39950605
Pan-modification profiling facilitates a cross-evolutionary dissection of the thermoregulated ribosomal epitranscriptome
Publikation
Garcia-Campos MA,
Georgeson J,
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(2025)
Cell, 188, 24, 6825-6844.e28, 10.1016/j.cell.2025.09.014, 41130207
Cell, 188, 24, 6825-6844.e28, 10.1016/j.cell.2025.09.014, 41130207
A resurrected ancestor of Cas12a expands target access and substrate recognition for nucleic acid editing and detection
Publikation
Jabalera Y,
Tascón I,
Samperio S,
López-Alonso JP,
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(2025)
Nature Biotechnology, 43, 10, 1663-1672, 10.1038/s41587-024-02461-3, 39482449
Nature Biotechnology, 43, 10, 1663-1672, 10.1038/s41587-024-02461-3, 39482449
Disparate mechanisms counteract extraneous CRISPR RNA production in type II-C CRISPR-Cas systems
Publikation
Feussner M,
Migur A,
Mitrofanov A,
Alkhnbashi OS,
Backofen R,
Beisel CL,
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(2025)
microLife, 6, uqaf007, 10.1093/femsml/uqaf007, 40376300
microLife, 6, uqaf007, 10.1093/femsml/uqaf007, 40376300
A Multicellular In Vitro Model of the Human Intestine with Immunocompetent Features Highlights Host-Pathogen Interactions During Early Salmonella Typhimurium Infection
Publikation
Damigos S,
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(2025)
Advanced Science, 12, 9, e2411233, 10.1002/advs.202411233, 39807570
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Proton-pump inhibitors increase C. difficile infection risk by altering pH rather than by affecting the gut microbiome based on a bioreactor model
Publikation
Schumacher J,
Müller P,
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(2025)
Gut Microbes, 17, 1, 2519697, 10.1080/19490976.2025.2519697, 40524314
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Allogeneic hematopoietic cell transplantation initiates atherosclerosis in mice via CD8+ T cells
Publikation
Jorgacevic I,
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Cardiovascular Research, 121, 17, 2668-2678, 10.1093/cvr/cvaf229, 41252283
Cardiovascular Research, 121, 17, 2668-2678, 10.1093/cvr/cvaf229, 41252283
High-Fidelity and Cost-Effective Engineering of SARS-CoV-2
Publikation
Olguin-Nava M,
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(2025)
Viruses, 17, 12, 1604, 10.3390/v17121604, 41472274
Viruses, 17, 12, 1604, 10.3390/v17121604, 41472274
A scalable gut epithelial organoid model reveals the genome-wide colonization landscape of a human-adapted pathogen
Publikation
Di Martino ML,
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Bhetwal A,
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Lopes ACC,
Ntokaki A,
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(2025)
Nature Genetics, 57, 7, 1730-1741, 10.1038/s41588-025-02218-x, 40506541
Nature Genetics, 57, 7, 1730-1741, 10.1038/s41588-025-02218-x, 40506541