Prof Franziska Faber


Franziska Faber studied biology at the Martin-Luther University (Halle/Saale, Germany). Her doctoral work at the Robert Koch Institute (Wernigerode, Germany) introduced her to the field of enteric bacterial infections. In 2011, she started her postdoctoral work in the lab of Andreas Bäumler at the University of California (Davis, USA). Here, she studied the mechanisms by which antibiotic treatment lowers “colonization resistance” against the enteric pathogen Salmonella  enterica. More specifically, she explored how inflammation-associated changes in intestinal nutrients contribute to intestinal colonization of S. enterica. In 2018, she joined the Center for Infectious Disease Research (ZINF) in Würzburg as a Young Investigator to study the previously unexplored RNA biology of the intestinal pathogen Clostridioides difficile. Since 2021, she has been a Junior Professor at the Institute of Molecular Infection Biology (IMIB) and has since headed the ROSE group at Julius-Maximilians-Universität (JMU) Würzburg, which is associated with the HIRI. In 2023, she was appointed to a W2 professorship at the Institute for Hygiene and Microbiology at JMU.


Durchfallerreger und die Homöostase der Mikrobiota

Winter S, Faber F, Bäumler A (2023)

BIOspektrum 29 (2): 127-129DOI: 10.1007/s12268-023-1901-3

A network of small RNAs regulates sporulation initiation in C difficile

Fuchs M, Lamm-Schmidt V, Lence T, Sulzer J, Bublitz A, Wackenreuter J, Gerovac M, Strowig T, Faber F (2023)

EMBO Journal 42 (12): e112858DOI: 10.15252/embj.2022112858


Grad-seq identifies KhpB as a global RNA-binding protein in Clostridioides difficile that regulates toxin production

Lamm-Schmidt V, Fuchs M, Sulzer J, Gerovac M, Hör J, Dersch P, Vogel J, Faber F (2021)

microLife 2: uqab004DOI: 10.1093/femsml/uqab004

Malaria parasite infection compromises colonization resistance to an enteric pathogen by reducing gastric acidity

Walker GT, Yang G, Tsai JY, Rodriguez JL, English BC, Faber F, Souvannaseng L, Butler BP, Tsolis RM (2021)

Science Advances 7 (27): eabd6232DOI: 10.1126/sciadv.abd6232

The metabolic footprint of Clostridia and Erysipelotrichia reveals their role in depleting sugar alcohols in the cecum

Tiffany CR, Lee JY, Rogers AWL, Olsan EE, Morales P, Faber F, Bäumler AJ (2021)

Microbiome 9 (1): 174DOI: 10.1186/s40168-021-01123-9

An RNA-centric global view of Clostridioides difficile reveals broad activity of Hfq in a clinically important gram-positive bacterium

Fuchs M, Lamm-Schmidt V, Sulzer J, Ponath F, Jenniches L, Kirk JA, Fagan RP, Barquist L, Vogel J, Faber F (2021)

PNAS 118 (25): e2103579118DOI: 10.1073/pnas.2103579118

RNA landscape of the emerging cancer-associated microbe Fusobacterium nucleatum

Ponath F, Tawk C, Zhu Y, Barquist L, Faber F, Vogel J (2021)

Nature Microbiology 6 (8): 1007-1020DOI: 10.1038/s41564-021-00927-7