Prof Franziska Faber
About
Franziska Faber studied biology at the Martin-Luther University (Halle/Saale, Germany). Her doctoral work at the Robert Koch Institute (Wernigerode, Germany) introduced her to the field of enteric bacterial infections. In 2011, she started her postdoctoral work in the lab of Andreas Bäumler at the University of California (Davis, USA). Here, she studied the mechanisms by which antibiotic treatment lowers “colonization resistance” against the enteric pathogen Salmonella enterica. More specifically, she explored how inflammation-associated changes in intestinal nutrients contribute to intestinal colonization of S. enterica. In 2018, she joined the Center for Infectious Disease Research (ZINF) in Würzburg as a Young Investigator to study the previously unexplored RNA biology of the intestinal pathogen Clostridioides difficile. Since 2021, she has been a Junior Professor at the Institute of Molecular Infection Biology (IMIB) and has since headed the ROSE group at Julius-Maximilians-Universität (JMU) Würzburg, which is associated with the HIRI. In 2023, she was appointed to a W2 professorship at the Institute for Hygiene and Microbiology at JMU.
2023
Durchfallerreger und die Homöostase der Mikrobiota
Winter S, Faber F, Bäumler A (2023)
BIOspektrum 29 (2): 127-129DOI: 10.1007/s12268-023-1901-3
A network of small RNAs regulates sporulation initiation in C difficile
Fuchs M, Lamm-Schmidt V, Lence T, Sulzer J, Bublitz A, Wackenreuter J, Gerovac M, Strowig T, Faber F (2023)
EMBO Journal 42 (12): e112858DOI: 10.15252/embj.2022112858
2021
Grad-seq identifies KhpB as a global RNA-binding protein in Clostridioides difficile that regulates toxin production
Lamm-Schmidt V, Fuchs M, Sulzer J, Gerovac M, Hör J, Dersch P, Vogel J, Faber F (2021)
microLife 2: uqab004DOI: 10.1093/femsml/uqab004
Malaria parasite infection compromises colonization resistance to an enteric pathogen by reducing gastric acidity
Walker GT, Yang G, Tsai JY, Rodriguez JL, English BC, Faber F, Souvannaseng L, Butler BP, Tsolis RM (2021)
Science Advances 7 (27): eabd6232DOI: 10.1126/sciadv.abd6232
The metabolic footprint of Clostridia and Erysipelotrichia reveals their role in depleting sugar alcohols in the cecum
Tiffany CR, Lee JY, Rogers AWL, Olsan EE, Morales P, Faber F, Bäumler AJ (2021)
Microbiome 9 (1): 174DOI: 10.1186/s40168-021-01123-9
An RNA-centric global view of Clostridioides difficile reveals broad activity of Hfq in a clinically important gram-positive bacterium
Fuchs M, Lamm-Schmidt V, Sulzer J, Ponath F, Jenniches L, Kirk JA, Fagan RP, Barquist L, Vogel J, Faber F (2021)
PNAS 118 (25): e2103579118DOI: 10.1073/pnas.2103579118
RNA landscape of the emerging cancer-associated microbe Fusobacterium nucleatum
Ponath F, Tawk C, Zhu Y, Barquist L, Faber F, Vogel J (2021)
Nature Microbiology 6 (8): 1007-1020DOI: 10.1038/s41564-021-00927-7