The Helmholtz Institute for RNA-based Infection Research in Würzburg combines interdisciplinary expertise with cutting-edge research infrastructure to exploit the vast potential of RNA as a diagnostic, target, and drug to understand, treat and prevent infectious diseases.
This illustration, created at the Centers for Disease Control and Prevention (CDC), reveals ultrastructural morphology exhibited by coronaviruses. Note the spikes that adorn the outer surface of the virus, which impart the look of a corona surrounding the virion, when viewed electron microscopically. A novel coronavirus, named Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2), was identified as the cause of an outbreak of respiratory illness first detected in Wuhan, China in 2019. The illness caused by this virus has been named coronavirus disease 2019 (COVID-19). Photo Credit: CDC/ Alissa Eckert, MS; Dan Higgins, MAMS
"Classical infection biology thinks in proteins. We focus on RNA."
– Jörg Vogel
Research at the HIRI focuses on four areas – bacterial infections, viral infections, host response and RNA delivery – complemented by the strategic pursuit of emerging topics in RNA research. Collaboration between groups is core to our mission and provides a vibrant research environment for our scientists and trainees.
“RNA is a powerful medium for engineering biology. We seek to better understand the fundamental properties of this biomolecule and how it can be harnessed to improve diagnosis and treatment of human infections.”
Be part of the future of RNA & Infection! Learn more about career opportunities at HIRI and find out about our current vacancies.