Successful dissertation on CRISPR-Cas
“RNA & Infection” graduate student Adini Arifah has defended her doctoral thesis
On July 6, Adini Arifah successfully defended her doctoral thesis. She joined the Helmholtz Institute Würzburg (HIRI) in 2021. As part of the graduate program “RNA & Infection,” she began her doctoral project, “Implications of tracrRNA–host RNA interactions for cytotoxicity and RNA engineering,” in the laboratory of HIRI department head Chase Beisel.
In the Beisel lab, Adini investigated the mechanisms underlying CRISPR-Cas9 cytotoxicity in bacteria and applied her findings to develop new CRISPR technologies.
During her master’s studies in biotechnology at Wageningen University in the Netherlands, Adini worked on the development of CRISPR tools for bacteria. She then continued this line of research as a research assistant at Wageningen University, where she focused on a control system for CRISPR-Cas tools based on a self-splicing intron riboswitch.
Congratulations, Adini!

























































































































































































































































































































































































